The Round of 64 matches of the 2021/22 edition of the MTN FA Cup commenced on Wednesday afternoon with some interesting results.

Hearts of Oak began their title defence with a 1-0 win over neighbours Accra Lions FC in the round of 64 fixture on Wednesday afternoon.

Aduana Stars defeated Eleven Wonders 4-1 to progress to the next stage of the competition.

A hat trick from Emmanuel Osei Baffour and a strike from Benjamin Tweneboah propelled the Dormaa based to a comfortable victory.

Great Olympics becomes the first Premier League casualty after suffering a suprise defeat against Real Athletico.

The lower tier side after 0-0 in regulation time won 3-1 on penalty

In Tamale, RTU survived a late scare to defeat Dreams Tamale in penalty shootout. The Premier League side after 1-1 in regulation time won 4-2 on penalties.

At the Gyandu Park, Premier League side Gold Stars defeated Sekondi Hasaacas 1-0 to progress to the round of 32. Michael Enu scored the only goal in the 6th minute.

The round of 64 games continue from Thursday to Sunday.

Below are results of matches played on Wednesday:

Aduana Stars 4-1 Eleven Wonders

Accra Lions 0-1 Hearts Of I Asa k

Sekondi Hasaacas 0-1 Bibiani Goldstars

Koforidua Suhyen 1-2 First Klaas

Real Athletico 1-1 Olympics
( Real won 3-1 on pen)

Tamale Dreams 1-1 RTU
( RTU won 4-2 on pen)