Hearts of Oak will lock horns with AshantiGold SC on Match Day 21 of the Ghana Premier League on Sunday.
The Phobians will be aiming to return to winning ways after their painful 0-1 defeat to Aduana Stars in Nana Agyemang Badu Park in Dormaa.
Hearts have not been able to beat the Miners in their last six league meetings, with Ashgold winning four and the other two ending in draws.
Coach Samuel Boadu has been handed a major injury boost following the return of Salifu Ibrahim, Enock Asuboteng, Kofi Kodzi and Sulley Ali Muntari ahead of this highly anticipated fixture.
However, the defending champions will be without goalkeeper Richard Attah who picked a groin injury against the Ogya Boys.
AshantiGold come into this game on the back of a convincing 2-0 win over King Faisal last week.
The Obuasi-based outfit are 11th on the league log with 25 points while Hearts of Oak are sitting 6th with 29 points after 20 league games.
The match is scheduled to kick off at 6:30pm at the Accra Sports Stadium.